At Oakland, the Broncos grabbed an early lead and never relinquished it to post the upset.
Ashley Danforth sparked Hampden Academy with 13 points, eight rebounds, five steals and three assists. Alex Winchester logged eight points and 10 rebounds and Jordan Maxwell added seven points.
Other HA scorers: Ellie Webb 3, Cassie Bean 2, Helene Sherburne 5, Elise Arsenault 3.
Megan Pelletier finished with 13 points to lead Messalonskee. Mary Badeen added seven.
Hampden 10 14 28 41
Messalonskee 7 12 21 30