At Fairfield, the Bulldogs outscored the Broncos 15-6 in the final period to erase a five-point deficit and earn the victory.
Nia Irving tossed in a game-high 21 points to propel Lawrence, while Dominique Lewis netted 10 points.
Alex Winchester and Erica Meehan paced Hampden Academy with nine points each.
Hampden 7 20 30 36
Lawrence 6 18 25 40