At Red Barry Gym in Bangor, the Rams shut out the Broncos in the first quarter and outscored the visitors 29-5 in the first half to record the victory.
Cordelia Stewart, Mary Butler and Jordan Seekins tossed in 12 points apiece in a balanced effort for Bangor.
Erica Meehan sparked Hampden Academy with 16 points.
Hampden 0 5 12 25
Bangor 13 29 42 53