At Ellsworth, Jonah Stephenson scored 21 points and Michael Boone added 13 as Presque Isle improved its record to 12-3.
Bradley Shields pulled down 10 rebounds for the Wildcats.
Ellsworth (4-10) was led by Steven Mahon 20 points and Nicholas Bagley 14 points.
Presque Isle (58): Nickerson-1-3-5, Stephenson-4-12-21, Norton-1-0-3, Boone 4-2-13, Eaton-1-6-8, Lyford-0-2-2, Shields-2-2-6
Ellsworth (48): Nightingale-1-2-4, B. Braley 1-0-2, Bean-1-2-4, Bagley-6-0-14, Mahon-7-4-20, Brooks-2-0-4
JV: Ellsworth 59-47