INDIANAPOLIS — Dan Orlovsky threw one touchdown pass and the key block on an 80-yard TD run, leading the Colts to their first win of the season, 27-13 over the Titans in NFL action Sunday.
Indianapolis (1-13) avoided becoming the second team in NFL history to go 0-16. The loss dealt a serious blow to the Titans’ playoff hopes. Quarterback Matt Hasselbeck was picked off twice and Chris Johnson rushed for only 55 yards for Tennessee (7-7).
Orlovsky gave Indy a 10-6 lead with an 18-yard TD pass to Reggie Wayne in the third quarter, and Jacob Lacey made it 17-6 with a 32-yard interception return for a TD.
Jake Locker got the Titans within 20-13 with a 7-yard TD pass to Nate Washington with 3:43 to go. But on the next play from scrimmage, with Donald Brown reversing field, Orlovsky threw a block that helped Brown get to the corner and sprint 80 yards to seal the win.
SEAHAWKS 38, BEARS 14
CHICAGO — Red Bryant returned an interception 20 yards for the go-ahead TD in the third quarter and Seattle kept its faint playoff hopes alive.
Chicago quarterback Caleb Hanie was hit hard on the play by K.J. Wright and threw the ball right into Bryant’s arms as Seattle (7-7) scored two TDs in a 50-second span early in the third quarter. Brandon Browner returned another interception 42 yards for a TD in the final quarter as the Seahawks outscored Chicago 31-0 in the second half.
Marshawn Lynch added two touchdown runs for Seattle.
Chicago (7-7) lost its fourth straight and played most of the game without wide receiver Johnny Knox, who was carted off the field after injuring his back while scrambling for a fumble early in the game.
SAINTS 42, VIKINGS 20
MINNEAPOLIS — Drew Brees threw for 412 yards and five touchdowns to New Orleans to its sixth win in a row.
Brees completed 32 of 40 passes to help the Saints (11-3) overcome a slow and sloppy start and stay two games ahead of Atlanta in the NFC South. Brees is 304 yards from breaking Dan Marino’s single-season record for yards passing with two games to play.
Brees threw two touchdown passes to Lance Moore and one each to Darren Sproles, Jimmy Graham and John Gilmore.
The maligned Saints pass defense held the Vikings to 94 yards passing. Adrian Peterson rushed for 60 yards in his return from a three-game absence for the Vikings (2-12).
PANTHERS 28, TEXANS 13
HOUSTON — Cam Newton threw two touchdown passes, DeAngelo Williams ran for a score and Carolina ended Houston’s seven-game winning streak.
Newton completed 13 of 23 passes for 149 yards, outplaying opposing rookie quarterback T.J. Yates. The Panthers (5-9) built a 21-0 halftime lead, then ended Houston’s second-half rally when linebacker James Anderson intercepted Yates in the end zone midway through the fourth quarter.
The Texans (10-4) are playing for home-field advantage in the playoffs after clinching the AFC South last weekend.
But their top-ranked defense looked vulnerable without coordinator Wade Phillips, who’s on medical leave after undergoing kidney and gall bladder surgery this week. Linebackers coach Reggie Herring made the defensive calls.
DOLPHINS 30, BILLS 23
ORCHARD PARK, N.Y. — Reggie Bush ran for a career-best 203 yards and touchdown to lead Miami to a 30-23 win over the Buffalo Bills in interim Dolphins coach Todd Bowles first game.
Bush sealed the win with a 76-yard touchdown run in the fourth quarter. Matt Moore threw two touchdowns passes, and Vontae Davis had two of Miami’s three interceptions.
Bowles replaced the fired Tony Sparano last Monday. Miami (5-9) has won five of seven.
The Bills (5-9) have lost seven straight and could finishing last in the AFC East for the fourth straight year. Ryan Fitzpatrick finished 31 of 47 for 316 yards and a TD.
BENGALS 20, RAMS 13
ST. LOUIS — Rookie A.J. Green had six catches and topped 1,000 yards for the season, and Cincinnati kept pace in the AFC playoff race.
Brandon Tate’s 56-yard punt return set up Bernard Scott’s go-ahead touchdown run late in the third quarter and Cedric Benson added a short scoring run in the fourth for the Bengals (8-6), who won for the second time in six games.
Green caught a 55-yarder to set up a field goal for the game’s first score. He has 1,006 yards receiving, leaving him 3 shy of Cris Collinsworth’s franchise rookie record in 1981.
Kellen Clemens was 25 for 36 for 229 and a late touchdown pass to Danario Alexander for the Rams (2-12), who have lost five in a row.